Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876478 | 0.88 | ADORA3 (0.36) | TP53 | |
| SCHEMBL8877982 | 0.85 | TP53 (0.34) | TP53 | |
| SCHEMBL8876797 | 0.81 | TP53 (0.33) | TP53 | |
| SCHEMBL8878409 | 0.79 | TP53 (0.36) | TP53 | |
| SCHEMBL8876250 | 0.79 | NR1I2 (0.39) | — | |
| SCHEMBL8876530 | 0.79 | HMGCR (0.34) | — | |
| SCHEMBL8877933 | 0.78 | HMGCR (0.41) | — | |
| SCHEMBL8878196 | 0.78 | TP53 (0.41) | TP53 | |
| SCHEMBL8877570 | 0.77 | HMGCR (0.40) | — | |
| SCHEMBL8900806 | 0.76 | ADORA3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |