Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878672 | 0.92 | MAPK1 (0.43) | MAPK1F10HPGDTSHRNPC1 | |
| SCHEMBL8876217 | 0.86 | MAPK1 (0.45) | MAPK1F10HPGDTSHR | |
| SCHEMBL7071160 | 0.85 | PLD1 (0.36) | PLD1 | |
| SCHEMBL7781108 | 0.83 | PLD1 (0.53) | PLD1 | |
| SCHEMBL8877715 | 0.83 | NPC1 (0.51) | PLD1TSHRNPC1ALDH1A1RAB9A | |
| SCHEMBL8877780 | 0.81 | KMT2A (0.41) | PLD1TSHRNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7774077 | 0.80 | PLD1 (0.53) | PLD1NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| Cyclopropane SCHEMBL7076457 | 0.80 | PLD1 (0.41) | PLD1TSHR | |
| Cyclopentane SCHEMBL7071125 | 0.80 | PLD1 (0.41) | PLD1TSHR | |
| Cyclohexane SCHEMBL7073239 | 0.80 | PLD1 (0.41) | PLD1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |