Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821823 | 0.97 | LTB4R (0.81) | LTB4RLTB4R2 | |
| SCHEMBL9198703 | 0.95 | LTB4R (0.77) | LTB4RLTB4R2 | |
| SCHEMBL9821890 | 0.94 | LTB4R (0.75) | LTB4RLTB4R2 | |
| SCHEMBL9198930 | 0.93 | LTB4R (0.75) | LTB4RLTB4R2 | |
| Sc-41390 SCHEMBL29403478 | 0.92 | LTB4R (1.00) | LTB4RLTB4R2 | |
| Sc-41390 SCHEMBL29369604 | 0.92 | LTB4R (1.00) | LTB4RLTB4R2 | |
| Sc-41390 SCHEMBL1889110 | 0.92 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9821822 | 0.91 | LTB4R (0.82) | LTB4RLTB4R2 | |
| SCHEMBL9192583 | 0.91 | LTB4R (0.71) | LTB4RLTB4R2 | |
| SCHEMBL8957165 | 0.91 | LTB4R (0.87) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292977-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLATE DERIVATIVES | G.D. Searle & Co. (US) | 1991-09-04 | — | — | EP | claimed |
| US-4889871-A | ANTIINFLAMMATORY AGENTS; SELECTIVE LEUKOTRIENE ANTAGONISTS | G. D. SEARLE & CO. (US) | 1989-12-26 | — | — | US | claimed |
| EP-0292977-A1 | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives | G.D. Searle & Co. (US) | 1988-11-30 | — | — | EP | claimed |
| US-5684162-A | BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1997-11-04 | — | — | US | disclosed |
| US-5578619-A | LEUKOTRIENE B4 ANTAGONISTS, ANTIINFLAMMATORY AGENTS | SEARLE & CO (US) | 1996-11-26 | — | — | US | disclosed |
| US-5532383-A | Leukotriene B4 antagonists | G. D. SEARLE & CO. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5516917-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1996-05-14 | — | — | US | disclosed |
| WO-1995033742-A1 | LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-12-14 | — | — | WO | disclosed |
| EP-0593478-B1 | LEUKOTRIENE B 4 ANTAGONISTS | SEARLE & CO (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1995032201-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-SULFONIMIDES DERIVATIVES, THEIR PREPARATION AND THEIR USE AS LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-11-30 | — | — | WO | disclosed |
| US-5439937-A | Leukotriene B4 antagonists | G. D. SEARLE & CO. (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0527922-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF. | SEARLE & CO (US) | 1993-02-24 | — | — | EP | disclosed |
| US-5124350-A | Antiinflammatory agent | G. D. SEARLE & CO. (US) | 1992-06-23 | — | — | US | disclosed |
| WO-1992000011-A2 | LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-01-09 | — | — | WO | disclosed |
| US-5073562-A | Antiinflammatory agents; leukotriene by antagonists | G. D. SEARLE & CO. (US) | 1991-12-17 | — | — | US | disclosed |
| WO-1991017160-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | disclosed |
| US-5051438-A | Treating leukotriene by mediated diseases; antiinflammatory agents | G. D. SEARLE & CO. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0292977-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLATE DERIVATIVES | G.D. Searle & Co. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4889871-A | ANTIINFLAMMATORY AGENTS; SELECTIVE LEUKOTRIENE ANTAGONISTS | G. D. SEARLE & CO. (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0292977-A1 | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives | G.D. Searle & Co. (US) | 1988-11-30 | — | — | EP | disclosed |