SCHEMBL887787

SCHEMBL887787

CC(C#N)OPOC(C)C#N.CC(C)NC(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8729468 0.73 TDP1 (0.40) TDP1TSHR
SCHEMBL7553220 0.68 TDP1 (0.35) TDP1
Acetonitrile SCHEMBL1526829 0.67 TDP1 (0.61) TDP1TSHR
Acetonitrile SCHEMBL953246 0.67 TDP1 (0.61) TDP1TSHR
Water SCHEMBL4030267 0.66
Acetonitrile SCHEMBL28125497 0.64 TDP1 (0.57) TDP1TSHR
SCHEMBL28239025 0.64 TDP1 (0.57) TDP1TSHR
Cyanate SCHEMBL28209292 0.64 TDP1 (0.57) TDP1TSHR
Water SCHEMBL28300228 0.62 TDP1 (0.80) TDP1
SCHEMBL25453160 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394944-B2 for detection and quantitation of single nucleotide polymorphisms (SNPs) using polymerase chain reaction (PCR); kits SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2013-03-12 US disclosed
US-8063196-B2 Highly orthogonal universal sequences for use in nucleic acid assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-11-22 US disclosed
US-7993838-B2 Nucleic acid primers and probes for detecting human and avian influenza viruses SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-08-09 US disclosed
US-20100330548-A1 Nucleic Acid Primers and Probes for Detecting Human and Avian Influenza Viruses SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2010-12-30 US disclosed
EP-2021516-B1 NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING HUMAN AND AVIAN INFLUENZA VIRUSES SIEMENS HEALTHCARE DIAGNOSTICS (US) 2010-10-20 EP disclosed
EP-1785491-B1 Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation SIEMENS HEALTHCARE DIAGNOSTICS (US) 2010-05-26 EP disclosed
US-20100047778-A1 Methylation Specific Primer Extension Assay for the Detection of Genomic Imprinting Disorders SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS (US) 2010-02-25 US disclosed
EP-2021516-A4 NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING HUMAN AND AVIAN INFLUENZA VIRUSES SIEMENS HEALTHCARE DIAGNOSTICS (US) 2009-05-20 EP disclosed
US-20090075273-A1 Planar Waveguide Detection Chips and Chambers for Performing Multiple PCR Assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-03-19 US disclosed
EP-2021516-A1 NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING HUMAN AND AVIAN INFLUENZA VIRUSES Siemens Healthcare Diagnostics Inc. (US) 2009-02-11 EP disclosed
EP-0795033-B1 DISCONTINUOUS PROBE DESIGN USING HYBRITOPE MAPPING BAYER AG (US) 2003-07-16 EP disclosed
US-5747248-A NUCLEOTIDE SEQUENCE IN TARGET NUCLEIC AND DETECTORS, LINKING AND BINDING CHIRON CORPORATION (US) 1998-05-05 US disclosed
US-5736327-A FOR DETECTING OR DETERMINING BINDING OLIGONUCLEOTIDE CHIRON CORPORATION (US) 1998-04-07 US disclosed
EP-0795033-A2 DISCONTINUOUS PROBE DESIGN USING HYBRITOPE MAPPING CHIRON CORPORATION (US) 1997-09-17 EP disclosed
US-5578717-A Nucleotides for introducing selectably cleavable and/or abasic sites into oligonucleotides CHIRON CORPORATION (US) 1996-11-26 US disclosed
US-5552538-A Oligonucleotides with cleavable sites CHIRON CORPORATION (US) 1996-09-03 US disclosed
US-5545730-A Multifunctional nucleic acid monomer CHIRON CORPORATION (US) 1996-08-13 US disclosed
WO-1996017955-A2 DISCONTINUOUS PROBE DESIGN USING HYBRITOPE MAPPING CHIRON CORPORATION (US) 1996-06-13 WO disclosed
US-5430136-A Oligonucleotides having selectably cleavable and/or abasic sites CHIRON CORPORATION (US) 1995-07-04 US disclosed
US-5258506-A Photolabile reagents for incorporation into oligonucleotide chains CHIRON CORPORATION (US) 1993-11-02 US disclosed