Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28300228 | 0.95 | TDP1 (0.80) | — | |
| SCHEMBL1332279 | 0.94 | — | — | |
| SCHEMBL2020 | 0.94 | — | — | |
| SCHEMBL27928984 | 0.94 | TDP1 (1.00) | — | |
| Methyl Alcohol SCHEMBL21933067 | 0.91 | TDP1 (0.73) | — | |
| Water SCHEMBL6817275 | 0.91 | TDP1 (0.73) | — | |
| SCHEMBL23451826 | 0.89 | — | — | |
| SCHEMBL381805 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL4464160 | 0.89 | — | — | |
| Ethane SCHEMBL22032756 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483746-B1 | Separation of methoxyisopropylamine from methoxyisopropylamine-water azeotrope | AIR PROD & CHEM (US) | 1995-06-28 | — | — | EP | claimed |
| US-5175369-A | Distillation and separation | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-12-29 | — | — | US | claimed |
| EP-0483746-A1 | Separation of methoxyisopropylamine from methoxyisopropylamine-water azeotrope | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-05-06 | — | — | EP | claimed |
| CN-119430214-A | Eutectic titanium silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-106413889-B | molecular sieve SSZ-99 | 雪佛龙美国公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-106457232-A | Process for preparing molecular sieve SSZ-99 | 雪佛龙美国公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106413889-A | Molecular sieve SSZ-99 | 雪佛龙美国公司 | 2017-02-15 | — | — | CN | disclosed |
| EP-1986694-B1 | COUPLING OF POLYPEPTIDES AT THE C-TERMINUS | NOVO NORDISK HEALTHCARE AG (CH) | 2015-06-10 | — | — | EP | disclosed |
| US-20140045753-A1 | COUPLING OF POLYPEPTIDES AT THE C-TERMINUS | NOVO NORDISK HEALTH CARE AG (CH) | 2014-02-13 | — | — | US | disclosed |
| US-20090155862-A1 | Process for the preparation of 2-hydroxymethyl-pyrrolidine-3,4-diols | LONZA AG (CH) | 2009-06-18 | — | — | US | disclosed |
| CN-100490084-C | Polishing liquid for CMP process and polishing method | SANYO CHEMICAL IND LTD (JP) | 2009-05-20 | — | — | CN | disclosed |
| US-20040185539-A1 | Process for the preparation of 2-hydroxymethyl-pyrolidine 3, 4-diols | LONZA AG (CH) | 2004-09-23 | — | — | US | disclosed |
| EP-1379676-A2 | PROCESS FOR THE PREPARATION OF 2-HYDROXYMETHYL-PYROLIDINE-3,4-DIOLS | LONZA AG (CH) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002074737-A2 | PROCESS FOR THE PREPARATION OF 2-HYDROXYMETHYL-PYROLIDINE-3,4-DIOLS | LONZA AG (CH) | 2002-09-26 | — | — | WO | disclosed |
| CN-1041054-C | Steroid 5-alpha-reductase inhibitors | SMITHKLINE BECKMAN CORP (US) | 1998-12-09 | — | — | CN | disclosed |
| EP-0483746-B1 | Separation of methoxyisopropylamine from methoxyisopropylamine-water azeotrope | AIR PROD & CHEM (US) | 1995-06-28 | — | — | EP | disclosed |
| CN-1026236-C | Steroid 5-alpha-reductase inhibitors | SMITHKLINE BECKMAN CORP (US) | 1994-10-19 | — | — | CN | disclosed |
| CN-1079747-A | The preparation of pharmaceutical compositions method that contains steroid 5-alpha-reductase inhibitors | SMITHKLINE BECKAMAN CORP (US) | 1993-12-22 | — | — | CN | disclosed |
| US-5175369-A | Distillation and separation | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0483746-A1 | Separation of methoxyisopropylamine from methoxyisopropylamine-water azeotrope | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-05-06 | — | — | EP | disclosed |