Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878710 | 0.91 | HMGCR (0.39) | HMGCRSQORGCGR | |
| SCHEMBL8877505 | 0.87 | HMGCR (0.40) | HMGCRSQORGCGR | |
| SCHEMBL8877739 | 0.84 | HMGCR (0.41) | HMGCRSQORGCGR | |
| SCHEMBL8876998 | 0.82 | HMGCR (0.38) | HMGCRSQORGCGR | |
| SCHEMBL8879127 | 0.78 | HMGCR (0.40) | HMGCRSQORGCGR | |
| SCHEMBL8877078 | 0.78 | HMGCR (0.39) | HMGCRSQOR | |
| SCHEMBL8877574 | 0.78 | HMGCR (0.39) | HMGCRGCGR | |
| SCHEMBL8877411 | 0.78 | HMGCR (0.40) | HMGCRSQORGCGR | |
| SCHEMBL8878963 | 0.77 | SQOR (0.38) | HMGCRSQORGCGR | |
| SCHEMBL8876833 | 0.77 | HMGCR (0.33) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |