Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 13/20 | 1.00 |
| ▸ | SLC6A15 | Q9H2J7 | 4/20 | 0.76 |
| ▸ | HRH1 | P35367 | 3/20 | 0.76 |
| ▸ | FNTA | P49354 | 3/20 | 0.76 |
| ▸ | FNTB | P49356 | 3/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.72 |
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374596 | 0.95 | PTAFR (0.91) | PTAFRSLC6A15HRH1FNTAFNTB | |
| SCHEMBL8880239 | 0.87 | PTAFR (1.00) | PTAFRSLC6A15HRH1FNTAFNTB | |
| SCHEMBL8879694 | 0.87 | PTAFR (1.00) | PTAFRSLC6A15HRH1FNTAFNTB | |
| SCHEMBL8879783 | 0.87 | PTAFR (0.77) | PTAFRSLC6A15HRH1FNTAFNTB | |
| SCHEMBL30056292 | 0.87 | HRH1 (0.80) | PTAFRSLC6A15HRH1FNTAFNTB | |
| SCHEMBL9073792 | 0.87 | HRH1 (0.80) | PTAFRSLC6A15HRH1FNTAFNTB | |
| SCHEMBL8879488 | 0.86 | PTAFR (1.00) | PTAFRSLC6A15HRH1FNTAFNTB | |
| Sch-37370 SCHEMBL3071641 | 0.86 | PTAFR (1.00) | PTAFRSLC6A15HRH1FNTAFNTB | |
| SCHEMBL6177676 | 0.86 | PTAFR (1.00) | PTAFRSLC6A15HRH1FNTAFNTB | |
| Sch-37370 SCHEMBL29626524 | 0.86 | PTAFR (1.00) | PTAFRSLC6A15HRH1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665726-A | ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0685476-A1 | Benzo(5,6)cycloheptapyridines, compositions and methods of use | SCHERING CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5438062-A | Antiallergens, antiinflammatory agents | SCHERING CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0270818-B1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORP (US) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993020063-A1 | UNBRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| US-4826853-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0270818-A1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |