SCHEMBL8877901

SCHEMBL8877901

NCCOCCNC(=O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 17/20 0.47
CA2 P00918 17/20 0.47
BLM P54132 2/20 0.47
PMP22 Q01453 2/20 0.47
HSD17B10 Q99714 1/20 0.47
CA4 P22748 6/20 0.46
CA12 O43570 3/20 0.46
CA9 Q16790 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2A P08913 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
DRD1 P21728 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
CYP2C19 P33261 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15508714 0.94 BLM (0.51) CA1CA2BLMPMP22HSD17B10
SCHEMBL15508733 0.94 BLM (0.51) CA1CA2BLMPMP22HSD17B10
SCHEMBL19172144 0.91 CA2 (0.42) CA1CA2BLMPMP22HSD17B10
SCHEMBL15508693 0.89 CA1 (0.46) CA1CA2BLMPMP22HSD17B10
SCHEMBL24297306 0.86 CA1 (0.47) CA1CA2BLMPMP22HSD17B10
SCHEMBL28682611 0.84 CA2 (0.36) CA1CA2CA4CA12CA9
SCHEMBL21539283 0.84 TDP1 (0.56) CA1CA2BLMPMP22CA4
SCHEMBL8719328 0.84 TDP1 (0.56) CA1CA2BLMPMP22CA4
SCHEMBL15499780 0.84 TDP1 (0.56) CA1CA2BLMPMP22CA4
SCHEMBL5547592 0.84 BLM (0.50) CA1CA2BLMPMP22HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5676923-A SOLUBLE, STABLE, ORGAN-SPECIFIC NUCLEAR MAGNETIC RESONANCE CONTRAST AGENT SCHERING AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed