Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878811 | 0.94 | BDKRB1 (0.40) | BDKRB1SLC6A3AGTR1AGTR2LTB4R2 | |
| SCHEMBL8873987 | 0.88 | BDKRB1 (0.41) | BDKRB1SLC6A3AGTR1AGTR2LTB4R2 | |
| SCHEMBL8872477 | 0.86 | MME (0.36) | AGTR1AGTR2 | |
| SCHEMBL8876246 | 0.86 | BDKRB1 (0.40) | BDKRB1SLC6A3AGTR1AGTR2LTB4R2 | |
| SCHEMBL8880408 | 0.83 | BDKRB1 (0.47) | BDKRB1SLC6A3AGTR1AGTR2LTB4R2 | |
| SCHEMBL8877163 | 0.81 | BDKRB1 (0.42) | BDKRB1SLC6A3AGTR1AGTR2LTB4R2 | |
| SCHEMBL8872885 | 0.79 | MME (0.37) | — | |
| SCHEMBL8878462 | 0.79 | BDKRB1 (0.42) | BDKRB1SLC6A3AGTR1AGTR2LTB4R2 | |
| SCHEMBL8879293 | 0.78 | SLC6A3 (0.38) | BDKRB1SLC6A3LTB4R2BRS3SLC6A4 | |
| SCHEMBL8872452 | 0.77 | MME (0.36) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608068-A | Process for the preparation of imidazopyridine derivatives and intermediates | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5557002-A | Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists | EISAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0627433-A1 | PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE | Eisai Co., Ltd. (JP) | 1994-12-07 | — | — | EP | disclosed |