SCHEMBL8877979

SCHEMBL8877979

CCON=C(CC)C1=C(O)CC(c2c(C)c(C)c3c(c2Cl)OC(C)(C)C3)CC1=O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8877970 1.00 RAB9A (0.36) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL8878508 0.92 RAB9A (0.38) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL8878502 0.92 RAB9A (0.38) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL8877762 0.92 RAB9A (0.38) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL8877755 0.92 RAB9A (0.38) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL8879545 0.90 RAB9A (0.38) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL8879552 0.90 RAB9A (0.38) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL8877981 0.86 RAB9A (0.30) RAB9A
SCHEMBL10792379 0.84 RAB9A (0.37) RAB9AKDM4EGAAMAPTALDH1A1
SCHEMBL10792373 0.84 RAB9A (0.37) RAB9AKDM4EGAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631208-A Herbicidal cyclohexane-1,3-dione derivatives and their preparation process KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-05-20 US claimed
US-5631208-A Herbicidal cyclohexane-1,3-dione derivatives and their preparation process KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-05-20 US disclosed