Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278115 | 0.88 | TDP1 (0.57) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL28092969 | 0.82 | KMT2A (0.64) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL222270 | 0.82 | TDP1 (0.67) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL2223541 | 0.79 | KMT2A (0.64) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL26215126 | 0.79 | KMT2A (0.56) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL4372575 | 0.79 | ERCC5 (0.63) | KMT2ATDP1MAPK1MAPTPOLB | |
| SCHEMBL1625685 | 0.78 | MAPT (0.49) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL17690536 | 0.77 | KMT2A (0.57) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL480106 | 0.77 | KMT2A (0.70) | KMT2ATDP1MAPK1GAAHTT | |
| SCHEMBL7778630 | 0.76 | MAPT (0.66) | KMT2ATDP1GAAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672708-A | Process for the preparation of N-arylaminoacrylic acid derivatives and the use of N-arylaminoacrylic acid derivatives thus prepared for the preparation of 4-quinolone-3-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |