Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877997 | 0.88 | KMT2A (0.57) | TDP1MAPTMAPK1POLBKMT2A | |
| SCHEMBL20767368 | 0.85 | SMN1; SMN2 (0.53) | TDP1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9080448 | 0.84 | SMN1; SMN2 (0.55) | MAPTMAPK1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6983176 | 0.84 | ALDH1A1 (0.55) | TDP1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL8490992 | 0.83 | TDP1 (0.70) | TDP1MAPTMAPK1POLBKMT2A | |
| SCHEMBL28092969 | 0.82 | KMT2A (0.64) | TDP1MAPTMAPK1POLBKMT2A | |
| SCHEMBL953973 | 0.80 | TDP1 (0.62) | TDP1MAPTMAPK1POLBKMT2A | |
| SCHEMBL29364863 | 0.80 | TDP1 (0.62) | TDP1MAPTMAPK1POLBKMT2A | |
| SCHEMBL31245529 | 0.79 | HPGD (0.53) | TDP1MAPTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL9860199 | 0.78 | ALDH1A1 (0.44) | MAPTMAPK1POLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739696-A1 | MITOCHONDRIA SPECIFIC TRANSCRIPTION INHIBITOR COMPOUNDS | Lunella Biotech, Inc. (CA) | 2026-05-13 | — | — | EP | disclosed |
| EP-4720079-A1 | MITOCHONDRIA SPECIFIC TRANSCRIPTION INHIBITORS | Lunella Biotech, Inc. (CA) | 2026-04-08 | — | — | EP | disclosed |
| US-20250206713-A1 | 2-[(2-OXO-4-PHENYL-2H-CHROMEN-7-YL)OXY] PROPANAMIDO DERIVATIVES | LUNELLA BIOTECH, INC. (CA) | 2025-06-26 | — | — | US | disclosed |
| EP-4499622-A1 | 2-[(2-OXO-4-PHENYL-2H-CHROMEN-7-YL)OXY] PROPANAMIDO DERIVATIVES | Lunella Biotech, Inc. (CA) | 2025-02-05 | — | — | EP | disclosed |
| WO-2025008773-A1 | MITOCHONDRIA SPECIFIC TRANSCRIPTION INHIBITOR COMPOUNDS | LUNELLA BIOTECH, INC. (CA) | 2025-01-09 | — | — | WO | disclosed |
| WO-2024246717-A1 | MITOCHONDRIA SPECIFIC TRANSCRIPTION INHIBITORS | LUNELLA BIOTECH, INC. (CA) | 2024-12-05 | — | — | WO | disclosed |
| CN-119072469-A | 2- [ (2-Oxo-4-phenyl-2H-chromen-7-yl) oxy ] propanamide derivatives | 卢内拉生物技术有限公司 | 2024-12-03 | — | — | CN | disclosed |
| WO-2023187561-A1 | 2-[(2-OXO-4-PHENYL-2H-CHROMEN-7-YL)OXY] PROPANAMIDO DERIVATIVES | LUNELLA BIOTECH, INC. (CA) | 2023-10-05 | — | — | WO | disclosed |
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206713-A1 | 2-[(2-OXO-4-PHENYL-2H-CHROMEN-7-YL)OXY] PROPANAMIDO DERIVATIVES | POLRMT, TFAM, POLM | TDP1 1398/4885MAPT 3452/4885MAPK1 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.