Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 16/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410718 | 0.97 | PTAFR (0.58) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 | |
| SCHEMBL10412015 | 0.85 | PTAFR (0.67) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 | |
| SCHEMBL25874350 | 0.84 | PTAFR (0.72) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 | |
| SCHEMBL9523592 | 0.84 | PTAFR (0.66) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 | |
| SCHEMBL10410495 | 0.83 | PTAFR (0.70) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9667471 | 0.83 | PTAFR (0.72) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9039332 | 0.82 | PTAFR (0.63) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 | |
| SCHEMBL9040170 | 0.82 | PTAFR (0.63) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 | |
| SCHEMBL10445676 | 0.81 | PTAFR (0.56) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 | |
| SCHEMBL9041476 | 0.81 | PTAFR (0.62) | PTAFRCYP3A4ALOX15TBXAS1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | claimed |
| EP-0328924-A2 | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-08-23 | — | — | EP | claimed |
| US-5593988-A | DIAZIPINE DERIVATIVES OF THIOPHENE FOR BONE DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-4937240-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-06-26 | — | — | US | disclosed |
| EP-0328924-A2 | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-08-23 | — | — | EP | disclosed |