Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785350 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL1435521 | 0.85 | RAB9A (0.59) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL27339512 | 0.85 | RAB9A (0.59) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8879495 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8880129 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9373000 | 0.84 | RAB9A (0.57) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8975518 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4805 | 0.83 | RAB9A (0.69) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL212382 | 0.82 | RAB9A (0.68) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL28091339 | 0.82 | RAB9A (0.68) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7010851-A | — | — | None | — | — | JP | disclosed |
| US-9382197-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20140275093-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-20110212969-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| EP-1553949-B1 | PYRIMIDINE-2,4-DIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2007-04-18 | — | — | EP | disclosed |
| US-7160893-B2 | Pyrimidine-2,4-dione derivatives as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160893-B2 | Pyrimidine-2,4-dione derivatives as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-5602160-A | MUSCLE RELAXANT | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1997-02-11 | — | — | US | disclosed |
| CN-1032001-C | Process for preparing aminoketones | MITSUI TOATSU CHEMICALS (JP) | 1996-06-12 | — | — | CN | disclosed |
| US-5498619-A | MUSCLE RELAXANTS, POLLAKIUREA CURING AGENTS AND MUSCLE SPASMS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-03-12 | — | — | US | disclosed |
| CN-1113488-A | Preparation process of aminoketones | MITSUI TOATSU CHEMICALS (JP) | 1995-12-20 | — | — | CN | disclosed |
| EP-0414391-B1 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS (JP) | 1995-03-15 | — | — | EP | disclosed |
| JP-H0710851-A | AMINOALCOHOL DERIVATIVE AND ITS USE | MITSUI TOATSU CHEM INC | 1995-01-13 | — | — | JP | disclosed |
| US-5338857-A | Muscle relaxant | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5194606-A | Reaction of amine with formaldehyde and ketone | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-03-16 | — | — | US | disclosed |
| US-5055585-A | Muscle relaxant | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-10-08 | — | — | US | disclosed |
| CN-1054596-A | Process for preparing aminoketones | MITSUI TOATSU CHEMICALS (JP) | 1991-09-18 | — | — | CN | disclosed |
| EP-0441621-A2 | Preparation process of aminoketones | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-08-14 | — | — | EP | disclosed |
| EP-0414391-A2 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275093-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC10, HDAC1 | SMN1; SMN2 975/4885RAB9A 2010/4885MEN1 3689/4885 |
| US-20110212969-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC10, HDAC1 | SMN1; SMN2 975/4885RAB9A 2010/4885MEN1 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.