Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 2/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.34 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.34 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.34 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.34 |
| ▸ | CACNA2D3 | Q8IZS8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876603 | 0.81 | HMGCR (0.34) | GCGR | |
| SCHEMBL8876731 | 0.81 | HMGCR (0.34) | GCGR | |
| SCHEMBL8877856 | 0.81 | HMGCR (0.37) | GCGR | |
| SCHEMBL8879008 | 0.80 | HMGCR (0.36) | GCGR | |
| SCHEMBL8877422 | 0.80 | — | — | |
| SCHEMBL8878938 | 0.79 | HMGCR (0.33) | GCGR | |
| SCHEMBL8876900 | 0.78 | GCGR (0.38) | GCGR | |
| SCHEMBL8878156 | 0.78 | HMGCR (0.35) | GCGR | |
| SCHEMBL8901153 | 0.78 | KDM4E (0.38) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL8876998 | 0.77 | HMGCR (0.38) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | claimed |