SCHEMBL8878720

SCHEMBL8878720

CCCOC(=O)c1ccc2c3cccc4cccc(c5ccc(C(=O)OCCC)c1c25)c43

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 3/20 0.46
HSD17B10 Q99714 3/20 0.46
MAOB P27338 2/20 0.46
LMNA P02545 2/20 0.45
TSHR P16473 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CDC25B P30305 2/20 0.43
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
PDK2 Q15119 1/20 0.41
CDC25A P30304 1/20 0.41
CDC25C P30307 1/20 0.41
ESR1 P03372 1/20 0.41
CHRM1 P11229 1/20 0.41
SLC6A2 P23975 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29613398 0.92 TSHR (0.56) ALDH1A1KDM4EHSD17B10LMNATSHR
SCHEMBL28848867 0.92 TSHR (0.56) ALDH1A1KDM4EHSD17B10LMNATSHR
SCHEMBL28641142 0.87 TSHR (0.51) ALDH1A1KDM4EHSD17B10LMNATSHR
SCHEMBL30463255 0.87 TSHR (0.51) ALDH1A1KDM4EHSD17B10LMNATSHR
SCHEMBL29113046 0.84 ALDH1A1 (0.56) ALDH1A1KDM4EHSD17B10MAOBLMNA
SCHEMBL9504146 0.82 ALDH1A1 (0.70) ALDH1A1KDM4EHSD17B10MAOBLMNA
SCHEMBL17934077 0.80 TSHR (0.64) ALDH1A1KDM4EHSD17B10LMNATSHR
SCHEMBL28174026 0.79 TSHR (0.49) ALDH1A1KDM4EHSD17B10LMNATSHR
SCHEMBL28289328 0.79 ALDH1A1 (0.62) ALDH1A1KDM4EHSD17B10MAOBLMNA
SCHEMBL2117339 0.78 ALDH1A1 (0.71) ALDH1A1KDM4EHSD17B10MAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650513-A Process for preparing perylene-3,4-dicarboxylic acid derivatives, the derivatives thus prepared and their use CIBA-GEIGY CORPORATION (US) 1997-07-22 US disclosed