⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22644635 | 0.94 | PRMT3 (0.31) | — | |
| SCHEMBL17449863 | 0.89 | — | — | |
| SCHEMBL16158824 | 0.89 | — | — | |
| SCHEMBL9887118 | 0.89 | HDAC3 (0.32) | — | |
| SCHEMBL19601268 | 0.88 | — | — | |
| SCHEMBL13703503 | 0.88 | — | — | |
| SCHEMBL18372007 | 0.86 | MEN1 (0.33) | — | |
| SCHEMBL26549795 | 0.86 | MEN1 (0.33) | — | |
| SCHEMBL26652081 | 0.84 | — | — | |
| SCHEMBL24227052 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067165-B2 | Binary probe and clamp composition and methods for target hybridization detection | APPLIED BIOSYSTEMS, LLC (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100291557-A1 | BINARY PROBE AND CLAMP COMPOSITION AND METHODS FOR TARGET HYBRIDIZATION DETECTION | Life Technologies Corporation (US) | 2010-11-18 | — | — | US | disclosed |
| US-20070026429-A1 | BINARY PROBE AND CLAMP COMPOSITION AND METHODS FOR TARGET HYBRIDIZATION DETECTION | APPLERA CORPORATION (US) | 2007-02-01 | — | — | US | disclosed |