SCHEMBL8879487

SCHEMBL8879487

CC(C)c1ccc(C(=O)O)c(C(=O)O)c1C(=O)O.[NaH]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 3/20 0.49
FABP3 P05413 1/20 0.47
FABP4 P15090 1/20 0.47
CYP1A2 P05177 1/20 0.39
ALDH1A1 P00352 2/20 0.39
GRM1 Q13255 1/20 0.39
SELL P14151 1/20 0.38
SELP P16109 1/20 0.38
EIF4A3 P38919 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALOX15 P16050 1/20 0.34
CSNK2A1 P68400 1/20 0.34
BCL2 P10415 1/20 0.34
MCL1 Q07820 1/20 0.34
NOTUM Q6P988 1/20 0.34
CDC25B P30305 1/20 0.33
GABRA1 P14867 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27588019 0.82 ACE2 (0.47) ACE2FABP3FABP4CYP1A2ALDH1A1
SCHEMBL5611626 0.82 ACE2 (0.47) ACE2FABP3FABP4CYP1A2ALDH1A1
SCHEMBL1446639 0.82 ACE2 (0.47) ACE2FABP3FABP4CYP1A2ALDH1A1
SCHEMBL8878681 0.82 ACE2 (0.40) ACE2FABP3FABP4CYP1A2ALDH1A1
SCHEMBL1356418 0.80 FABP3 (0.47) ACE2FABP3FABP4CYP1A2ALDH1A1
SCHEMBL8879805 0.80 CYP1A2 (0.58) CYP1A2ALDH1A1SELLSELPMAPT
SCHEMBL343203 0.78 FABP3 (0.46) ACE2FABP3FABP4CYP1A2ALDH1A1
SCHEMBL22989 0.78 CYP1A2 (0.61) CYP1A2ALDH1A1SELLSELPMAPT
SCHEMBL1988762 0.78 CYP1A2 (0.61) CYP1A2ALDH1A1SELLSELPMAPT
SCHEMBL29445717 0.78 CYP1A2 (0.61) CYP1A2ALDH1A1SELLSELPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639922-A CONTACTING AROMATIC PRIMARY AND TERTIARY HYDROPEROXIDES MIXTURE OBTAINED BY OXIDATION OF ALKYLAROMATIC COMPOUNDS WITH AN ALKALI OR ALKALINE ORGANIC AROMATIC CARBOXYLIC ACID SALT, DECOMPOSING WITH ACID CATALYST FORMING ALKYL PHENOLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-17 US disclosed