Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 8/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 10/20 | 0.57 |
| ▸ | HTR1D | P28221 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880006 | 0.85 | HTR1B (0.56) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL1388907 | 0.82 | HTR1B (0.67) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL1388908 | 0.82 | HTR1B (0.67) | HTR1BHTR1AHTR6HTR1D | |
| Hydrochloric Acid SCHEMBL8612746 | 0.81 | HTR1B (0.66) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8932357 | 0.80 | HTR1B (0.76) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8932358 | 0.80 | HTR1B (0.76) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL7465779 | 0.80 | HTR1B (0.61) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8879855 | 0.79 | HTR1B (0.72) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL7465775 | 0.79 | HTR1B (0.62) | HTR1BHTR1AHTR6HTR1D | |
| SCHEMBL8617260 | 0.79 | HTR1B (0.70) | HTR1BHTR1AHTR6HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046525-A1 | 5-ALKOXY-TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR AGONISTS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-12-11 | — | — | WO | claimed |
| US-5654431-A | EXHIBIT SELECTIVITY TOWARDS 5-HYDROXYTRYPTAMINE RECEPTORS OF BRAIN CELLS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-08-05 | — | — | US | claimed |