Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204216 | 0.82 | PARP1 (0.58) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL11210705 | 0.81 | PARP1 (0.56) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL19436979 | 0.79 | PARP1 (0.50) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL29030849 | 0.78 | PARP1 (0.49) | PARP1NPSR1TDP1 | |
| SCHEMBL15557200 | 0.78 | PARP1 (0.51) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL28174605 | 0.78 | PARP1 (0.51) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL242552 | 0.77 | PARP1 (0.40) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL241061 | 0.77 | PARP1 (0.42) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL21616783 | 0.77 | PARP1 (0.50) | PARP1NPSR1MEN1PKMKMT2A | |
| SCHEMBL8880740 | 0.77 | PARP1 (0.50) | PARP1NPSR1MEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046525-A1 | 5-ALKOXY-TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR AGONISTS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-12-11 | — | — | WO | disclosed |
| US-5654431-A | EXHIBIT SELECTIVITY TOWARDS 5-HYDROXYTRYPTAMINE RECEPTORS OF BRAIN CELLS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-08-05 | — | — | US | disclosed |