Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632483 | 0.97 | TDP1 (0.63) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Hydrochloric Acid SCHEMBL10705435 | 0.97 | LMNA (0.58) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL7178468 | 0.97 | TDP1 (0.63) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL27551635 | 0.92 | — | — | |
| Mannitol SCHEMBL9456465 | 0.82 | LMNA (0.79) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL27688199 | 0.81 | LMNA (0.58) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL15209529 | 0.79 | — | — | |
| Mannitol SCHEMBL5050555 | 0.79 | LMNA (0.73) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL21327681 | 0.79 | LMNA (0.73) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL1132477 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137514-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN PREVENTING AND TREATING OBESITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1988-09-21 | — | — | EP | claimed |
| EP-0137514-A2 | Compounds and compositions for use in preventing and treating obesity | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-04-17 | — | — | EP | claimed |
| EP-0041896-B1 | IMMUNOLOGICALLY ACTIVE DIPEPTIDYL 2-AMINO-1,2-DIDEOXY-D-GLUCOSE DERIVATIVES AND METHODS OF PREPARATION | MERCK & CO. INC. (US) | 1983-12-28 | — | — | EP | claimed |
| US-4315913-A | BACTERICIDES, VIRICIDES, PARASITICIDES VACCINE | MERCK & CO. INC. (US) | 1982-02-16 | — | — | US | claimed |
| EP-0041896-A1 | Immunologically active dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives and methods of preparation | MERCK & CO. INC. (US) | 1981-12-16 | — | — | EP | claimed |
| JP-60081127-A | — | — | None | — | — | JP | disclosed |
| US-20130336943-A1 | MEANS AND METHODS FOR ACTIVATING VAGUS NERVE | CALPIS CO., LTD. (JP) | 2013-12-19 | — | — | US | disclosed |
| US-20120009163-A1 | MEANS AND METHODS FOR ACTIVATING VAGUS NERVE | CALPIS CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
| US-6630146-B2 | For treatment of disseminated candidiasis due to infection by C.albicans; monoclonal antibodies for use in passive immunization against candidal infections | MONTANA STATE UNIVERSITY | 2003-10-07 | — | — | US | disclosed |
| US-20030072775-A1 | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine | THE RESEARCH AND DEVELOPMENT INSTITUTE INC. | 2003-04-17 | — | — | US | disclosed |
| US-6488929-B2 | FOR TREATMENT OF DISSEMINATED CANDIDIASIS DUE TO INFECTION BY C. ALBICANS; COMPOSITION INCLUDES PHOSPHOMANNAN OF C. ALBICANS | MONTANA STATE UNIVERSITY | 2002-12-03 | — | — | US | disclosed |
| US-20020160009-A1 | CANDIDA ALBICANS PHOSHOMANNAN COMPLEX AS A VACCINE | MORGAN, LEWIS AND BOCKUIS LLP | 2002-10-31 | — | — | US | disclosed |
| US-4868157-A | IMMUNOLOGY | MERCK & CO., INC. (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0137514-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN PREVENTING AND TREATING OBESITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1988-09-21 | — | — | EP | disclosed |
| US-4696919-A | APPETITE SUPPRESSANTS WITH GLUCOSAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-09-29 | — | — | US | disclosed |
| JP-S6081127-A | APPETITE-SUPPRESSING AGENT | CHUGAI PHARMACEUT CO LTD | 1985-05-09 | — | — | JP | disclosed |
| EP-0137514-A2 | Compounds and compositions for use in preventing and treating obesity | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-04-17 | — | — | EP | disclosed |
| EP-0041896-B1 | IMMUNOLOGICALLY ACTIVE DIPEPTIDYL 2-AMINO-1,2-DIDEOXY-D-GLUCOSE DERIVATIVES AND METHODS OF PREPARATION | MERCK & CO. INC. (US) | 1983-12-28 | — | — | EP | disclosed |
| US-4315913-A | BACTERICIDES, VIRICIDES, PARASITICIDES VACCINE | MERCK & CO. INC. (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0041896-A1 | Immunologically active dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives and methods of preparation | MERCK & CO. INC. (US) | 1981-12-16 | — | — | EP | disclosed |