Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8879902 | 0.99 | ADRB2 (0.98) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL3585936 | 0.90 | ADRB2 (1.00) | ADRB2 | |
| SCHEMBL3596833 | 0.90 | ADRB2 (0.89) | ADRB2 | |
| SCHEMBL3584505 | 0.89 | ADRB2 (0.86) | ADRB2 | |
| SCHEMBL3582012 | 0.89 | ADRB2 (0.80) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL3581965 | 0.88 | ADRB2 (0.88) | ADRB2ABCB11 | |
| SCHEMBL3592448 | 0.87 | ADRB2 (1.00) | ADRB2 | |
| SCHEMBL3596653 | 0.87 | ADRB2 (0.84) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL3583972 | 0.86 | ADRB2 (0.81) | ADRB2 | |
| SCHEMBL4218617 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648370-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-07-15 | — | — | US | claimed |