Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830102 | 0.86 | TOP2A (0.45) | L3MBTL1TOP2AMAPTKAT2BPLAU | |
| SCHEMBL1751588 | 0.85 | MAPT (0.56) | L3MBTL1TOP2AMAPTEGFRMEN1 | |
| SCHEMBL658049 | 0.84 | MAPT (0.59) | L3MBTL1TOP2AMAPTMEN1HPGD | |
| SCHEMBL9271365 | 0.83 | HTT (0.50) | L3MBTL1MAPTMEN1HPGDKMT2A | |
| SCHEMBL16302283 | 0.83 | TOP2A (0.48) | L3MBTL1TOP2AMAPTALDH1A1MGAM | |
| SCHEMBL4865806 | 0.83 | TOP2A (0.48) | TOP2AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9829293 | 0.83 | ABCB1 (0.51) | L3MBTL1TOP2AMAPTKAT2BPLAU | |
| SCHEMBL9830975 | 0.82 | TOP2A (0.47) | L3MBTL1TOP2AMAPTALDH1A1MGAM | |
| SCHEMBL27943015 | 0.81 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9832154 | 0.81 | CYP1A2 (0.46) | TOP2AMAPTEGFRHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689927-B | Phenoxyquinoline and synthesis method thereof | 陕西恒润化学工业有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-108689927-A | A kind of quinoxyfen and its synthetic method | 陕西恒润化学工业有限公司 | 2018-10-23 | — | — | CN | claimed |
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |
| CN-108689927-B | Phenoxyquinoline and synthesis method thereof | 陕西恒润化学工业有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-108689927-A | A kind of quinoxyfen and its synthetic method | 陕西恒润化学工业有限公司 | 2018-10-23 | — | — | CN | disclosed |
| US-5599813-A | ANTIANGIOGENIC AGENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0618208-A1 | Thiazolopyrimidine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4925939-A | 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-05-15 | — | — | US | disclosed |