Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 7/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PTPRB | P23467 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRG | P23470 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509018 | 0.89 | PTPRB (0.47) | PTPRBCA2PTPN2PTPN1PTPRA | |
| SCHEMBL8879088 | 0.85 | MEN1 (0.44) | CYP4A11CYP4F2PTPRBBRS3PTPN2 | |
| SCHEMBL11646444 | 0.84 | PTPRB (0.44) | PTPRBPTPN2PTPN1PTPRA | |
| SCHEMBL15059305 | 0.82 | EPHX2 (0.44) | PTPRBPTPN2PTPN1PTPRA | |
| SCHEMBL11530777 | 0.82 | HPGD (0.45) | PTPRBPTPN2PTPN1PTPRA | |
| SCHEMBL3665931 | 0.82 | ESR1 (0.53) | PTPRBCA2PTPN2PTPN1PTPRA | |
| SCHEMBL14290217 | 0.82 | ALDH1A1 (0.45) | PTPRBCA2PTPN2PTPN1PTPRA | |
| SCHEMBL6469058 | 0.81 | GRN (0.50) | PPARAPTPRB | |
| SCHEMBL18999227 | 0.81 | CA1 (0.51) | CA2PTPN1CA1 | |
| SCHEMBL13903099 | 0.81 | PTPRB (0.54) | PTPRBCA2CA1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624948-A | TREATMENT OF BRONCHIAL ASTHMA | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0699668-A1 | 1-(2-BENZIMIDAZOLYL)-1,5-DIAZACYCLOOCTANE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 1996-03-06 | — | — | EP | disclosed |