Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.55 |
| ▸ | PRKDC | P78527 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883242 | 0.93 | MEN1 (0.49) | P2RY12PRKDCMEN1KMT2A | |
| SCHEMBL8882570 | 0.92 | MEN1 (0.50) | P2RY12PRKDCMEN1KMT2AKDM4E | |
| SCHEMBL8881588 | 0.87 | ABCB1 (0.47) | P2RY12PRKDCMEN1KMT2A | |
| SCHEMBL8882846 | 0.87 | PRKDC (0.51) | P2RY12PRKDCMEN1KMT2A | |
| SCHEMBL8880007 | 0.86 | HTR7 (0.45) | PRKDCMEN1KMT2A | |
| SCHEMBL8883230 | 0.85 | PRKDC (0.49) | P2RY12PRKDCMEN1KMT2A | |
| SCHEMBL8881710 | 0.85 | MEN1 (0.45) | P2RY12PRKDCMEN1KMT2A | |
| SCHEMBL8881292 | 0.83 | PRKDC (0.47) | P2RY12PRKDCMEN1KMT2AKDM4E | |
| SCHEMBL8884463 | 0.82 | PRKDC (0.40) | P2RY12PRKDCMEN1KMT2AALDH1A1 | |
| SCHEMBL7326772 | 0.81 | P2RY12 (0.48) | P2RY12PRKDCKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | claimed |
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |