⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9676640 | 0.99 | — | — | |
| SCHEMBL9676012 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL9675471 | 0.98 | — | — | |
| SCHEMBL9676291 | 0.98 | — | — | |
| SCHEMBL9676584 | 0.97 | — | — | |
| SCHEMBL9676313 | 0.95 | CHRM2 (0.51) | — | |
| SCHEMBL9673959 | 0.95 | CHRM2 (0.54) | — | |
| Hydrochloric Acid SCHEMBL9673831 | 0.94 | LMNA (0.54) | — | |
| SCHEMBL9674043 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL9675612 | 0.94 | LMNA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306698-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1992-03-25 | — | — | EP | claimed |
| EP-0306698-A1 | Condensed diazepinones, processes for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1989-03-15 | — | — | EP | claimed |
| US-5641772-A | Condensed diazepinones, processes for preparing them and agents containing these compounds for treating diseases of the central nervous system and for promoting cerebral blood circulation | DR. KARL THOMAE GMBH (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5610155-A | ALZHEIMER'S | DR. KARL THOMAE GMBH (DE) | 1997-03-11 | — | — | US | disclosed |
| EP-0508370-B1 | Condensed diazepinones, process for their preparation and compositions containing them for the treatment of the central nervous system and to enhance cerebral perfusion | THOMAE GMBH DR K (DE) | 1996-07-03 | — | — | EP | disclosed |
| EP-0508370-A1 | Condensed diazepinones, process for their preparation and compositions containing them for the treatment of the central nervous system and to enhance cerebral perfusion | Dr. Karl Thomae GmbH (DE) | 1992-10-14 | — | — | EP | disclosed |
| EP-0306698-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1992-03-25 | — | — | EP | disclosed |
| EP-0402734-A2 | Composition for the treatment of application of the central nervous system and to enhance cerebral perfusion | Dr. Karl Thomae GmbH (DE) | 1990-12-19 | — | — | EP | disclosed |
| US-4931436-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0306698-A1 | Condensed diazepinones, processes for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1989-03-15 | — | — | EP | disclosed |