Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.64 |
| ▸ | CCR3 | P51677 | 3/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10719501 | 0.83 | BCHE (0.49) | KCNA3CCR3ACHEBCHE | |
| Hydrochloric Acid SCHEMBL10718577 | 0.83 | KCNA3 (0.54) | KCNA3CCR3CHRM3CHRM2CHRM1 | |
| SCHEMBL10519952 | 0.79 | CCR3 (0.59) | CCR3CHRM3CHRM2CHRM1ACHE | |
| SCHEMBL803462 | 0.79 | CCR3 (0.67) | CCR3ACHEALDH1A1CXCR4BCHE | |
| SCHEMBL4186493 | 0.78 | KCNA3 (0.55) | KCNA3CCR3CHRM3CHRM2CHRM1 | |
| SCHEMBL6749208 | 0.78 | CCR3 (0.54) | CCR3ACHEALDH1A1CXCR4BCHE | |
| SCHEMBL4757519 | 0.78 | KCNA3 (0.54) | KCNA3CCR3CHRM3CHRM2CHRM1 | |
| SCHEMBL3975039 | 0.78 | CHRM3 (0.69) | KCNA3CCR3CHRM3CHRM2CHRM1 | |
| SCHEMBL12794683 | 0.78 | CHRM3 (0.69) | KCNA3CCR3CHRM3CHRM2CHRM1 | |
| SCHEMBL10316373 | 0.78 | CHRM3 (0.69) | KCNA3CCR3CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607950-A | IRRITABLE BOWEL SYNDROME | PFIZER INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0508988-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0508988-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1992-10-21 | — | — | EP | disclosed |
| WO-1991010647-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |