Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632755 | 0.83 | ACHE (0.51) | ACHEBCHE | |
| SCHEMBL803462 | 0.81 | CCR3 (0.67) | CCR3CXCR4ACHEBCHEALDH1A1 | |
| SCHEMBL8880481 | 0.79 | KCNA3 (0.64) | CCR3CHRM3CXCR4ACHEBCHE | |
| SCHEMBL8878260 | 0.79 | CHRM3 (0.56) | CCR3CHRM3CXCR4ACHEBCHE | |
| SCHEMBL15140944 | 0.79 | CCR3 (0.73) | CCR3CXCR4ACHEBCHEALDH1A1 | |
| SCHEMBL6362147 | 0.78 | KCNH2 (0.83) | CHRM3ACHEKCNH2HRH1ALDH1A1 | |
| SCHEMBL6749556 | 0.78 | CCR3 (0.58) | CCR3CXCR4ACHEBCHEALDH1A1 | |
| SCHEMBL368874 | 0.78 | CCR3 (0.67) | CCR3CXCR4ACHEBCHEALDH1A1 | |
| SCHEMBL349053 | 0.77 | CCR3 (0.71) | CCR3CXCR4ACHEBCHEALDH1A1 | |
| SCHEMBL3107807 | 0.77 | CCR3 (0.71) | CCR3CXCR4ACHEBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309424-A2 | New amidino derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |