Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8879883 | 0.99 | KMT2A (0.49) | KMT2APOLBCHRM3CHRM2CACNA2D1 | |
| SCHEMBL1641984 | 0.79 | POLB (0.51) | KMT2APOLBCHRM3CHRM2CYP2D6 | |
| SCHEMBL8879197 | 0.73 | KCNA3 (0.49) | KMT2APOLBCHRM3CYP2D6KCNH2 | |
| SCHEMBL465843 | 0.73 | POLB (0.48) | KMT2APOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL22260272 | 0.72 | CYP2D6 (0.48) | KMT2APOLBCYP2D6LMNAKDM4E | |
| SCHEMBL20833005 | 0.72 | CYP2D6 (0.48) | KMT2APOLBCYP2D6LMNAKDM4E | |
| SCHEMBL6053465 | 0.72 | POLB (0.47) | KMT2APOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL678496 | 0.72 | KDM4E (0.41) | KMT2APOLBCHRM3CHRM2CYP2D6 | |
| SCHEMBL27886943 | 0.72 | GHSR (0.42) | KMT2APOLBCHRM3CYP2D6KDM4E | |
| SCHEMBL27886944 | 0.72 | GHSR (0.42) | KMT2APOLBCHRM3CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607950-A | IRRITABLE BOWEL SYNDROME | PFIZER INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0508988-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0508988-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1992-10-21 | — | — | EP | disclosed |
| WO-1991010647-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |