⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990439 | 0.77 | — | — | |
| Bromide SCHEMBL11815339 | 0.76 | — | — | |
| SCHEMBL14029055 | 0.70 | — | — | |
| SCHEMBL23328232 | 0.68 | — | — | |
| SCHEMBL12322123 | 0.68 | — | — | |
| SCHEMBL14029047 | 0.67 | NISCH (0.41) | — | |
| SCHEMBL19670968 | 0.60 | — | — | |
| SCHEMBL6318998 | 0.55 | — | — | |
| SCHEMBL15074779 | 0.53 | — | — | |
| SCHEMBL24031520 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599813-A | ANTIANGIOGENIC AGENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0618208-A1 | Thiazolopyrimidine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0034250-A1 | Preparation of 5,5-dimethyl-2-hydrazino-1,4,5,6-tetrahydropyrimidine hydrohalide | AMERICAN CYANAMID COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4262122-A | Preparation of 5,5-dimethyl-2-hydrazino-1,4,5,6-tetrahydro-pyrimidine hydrohalide | AMERICAN CYANAMID COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-RE29358-E | ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-08-16 | — | — | US | disclosed |