⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11815339 | 0.98 | — | — | |
| Iodide SCHEMBL2414539 | 0.98 | — | — | |
| SCHEMBL8880798 | 0.77 | — | — | |
| Iodide SCHEMBL11279975 | 0.75 | — | — | |
| SCHEMBL34472928 | 0.72 | — | — | |
| Bromide SCHEMBL11698382 | 0.71 | PTGIR (0.30) | — | |
| SCHEMBL13024396 | 0.70 | — | — | |
| SCHEMBL3541111 | 0.68 | — | — | |
| SCHEMBL14029055 | 0.67 | — | — | |
| Iodide SCHEMBL10795714 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339947-A1 | USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS | Madera Therapeutics, LLC | 2023-10-26 | — | — | US | disclosed |
| US-20230339947-A1 | USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS | Madera Therapeutics, LLC | 2023-10-26 | — | — | US | disclosed |
| EP-2275100-A2 | Compounds with anti-parasitic activity and drugs containing said compounds | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-01-19 | — | — | EP | disclosed |
| EP-2266555-A2 | Compounds with antiparasitic activity and medicines containing same | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-12-29 | — | — | EP | disclosed |
| EP-2260841-A2 | Compounds with antiparasitic activity and medicines containing same | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260840-A2 | Compounds with antiparasitic activity and medicines containing same | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-12-15 | — | — | EP | disclosed |
| EP-1524972-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY AND MEDICINES CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004009068-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY AND MEDICINES CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2004-01-29 | — | — | WO | disclosed |