Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.54 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690019 | 0.91 | HRH2 (0.52) | ITGB3ITGA2BITGAVP2RX7HRH2 | |
| SCHEMBL8880131 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL8880135 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL8880972 | 0.87 | ITGB3 (0.60) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL8519246 | 0.86 | ITGB3 (0.67) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL7276503 | 0.82 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL9281663 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BP2RX7 | |
| SCHEMBL8881449 | 0.80 | HRH2 (0.49) | ITGB3ITGA2BHRH2HRH1 | |
| SCHEMBL2007668 | 0.80 | ITGB3 (0.58) | ITGB3ITGA2BP2RX7 | |
| SCHEMBL22756121 | 0.80 | ITGB3 (0.55) | ITGB3ITGA2BITGAVP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658928-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS,WOUND HEALING AGENTS, OSTEOPOROSIS | HOFFMANN-LA ROCHE INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5545658-A | FOR TREATMENT OR PROPHYLAXIS OF ILLNESSES WHICH ARE CAUSED BY THE BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELETS AND BY BLOOD PLATELET AGGREGATION AND CELL-CELL ADHESION | HOFFMAN-LA ROCHE INC. (US) | 1996-08-13 | — | — | US | disclosed |