Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 6/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879654 | 1.00 | TAAR1 (0.38) | TAAR1DPP4XIAPBIRC2CTRB1 | |
| SCHEMBL8879521 | 1.00 | TAAR1 (0.38) | TAAR1DPP4XIAPBIRC2CTRB1 | |
| Hydrochloric Acid SCHEMBL8880539 | 0.98 | TAAR1 (0.37) | TAAR1DPP4XIAPBIRC2CTRB1 | |
| SCHEMBL8878814 | 0.75 | ESR2 (0.34) | — | |
| SCHEMBL8878827 | 0.75 | ESR2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8880303 | 0.74 | KDM4E (0.36) | — | |
| SCHEMBL8878956 | 0.71 | TDP1 (0.32) | — | |
| SCHEMBL5610745 | 0.69 | — | — | |
| SCHEMBL1258017 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL27321584 | 0.67 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605925-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| US-5580987-A | TREATING 1-PHTHALIMIDOPYRROLE WITH BASE TO YIELD 1-AMINOPYRROLE, REACTING WITH SUBSTITUTED AMINO ACID TO OBTAIN DESIRED COMPOUND | HOECHST MARION ROUSSEL, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5576446-A | GLYCINE PARTIAL AGONIST AND ENHANCEMENT OF LEARNING AND MEMORY, TREATMENT OF ALZHEIMER'S | HOECHST MARION ROUSSEL, INC. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5428053-A | Treats alzheimer's disease and other senile dementias | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0582182-A1 | 1-Aminoacetamidopyrroles and 1-amino-2-(substituted) pyrroles and their use for the treatment of neurodegenerative dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-02-09 | — | — | EP | disclosed |
| US-5274116-A | 1-aminoacetamidopyrroles and 1-aminoacetamido-2-(substituted)pyrroles and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-12-28 | — | — | US | disclosed |