Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.43 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888156 | 0.89 | POLB (0.48) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL888142 | 0.88 | POLB (0.44) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL888099 | 0.86 | ENPP1 (0.52) | POLBENPP1P2RY1 | |
| SCHEMBL1140532 | 0.80 | P2RY12 (0.54) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL888084 | 0.80 | POLB (0.47) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL14665951 | 0.78 | P2RX3 (0.53) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL30848930 | 0.78 | P2RX3 (0.53) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL888262 | 0.78 | P2RX3 (0.53) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL21564046 | 0.78 | P2RX3 (0.53) | POLBP2RX1P2RX3P2RX2P2RX4 | |
| SCHEMBL888089 | 0.78 | P2RX3 (0.53) | POLBP2RX1P2RX3P2RX2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287427-A1 | 3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-7964352-B2 | 3′-OH unblocked nucleotides and nucleosides, base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-7897737-B2 | Polymorphic identification; fluorescent dyes | LASERGEN, INC. (US) | 2011-03-01 | — | — | US | disclosed |