SCHEMBL888170

CC(C)(C)OC(=O)N(Cc1ccc(C#CCNC(=O)C(F)(F)F)cc1[N+](=O)[O-])c1ncnc2c1ncn2[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)O1

nearest known ligand 0.32

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	ADRA2A	P08913	1/20	0.32

▸	DRD5	P21918	1/20	0.32

▸	DRD3	P35462	1/20	0.32

▸	P2RY6	Q15077	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12762667	0.92	ADRA2A (0.32)	ADRA2ADRD5DRD3P2RY6
SCHEMBL12570166	0.92	ADRA2A (0.32)	ADRA2ADRD5DRD3P2RY6
SCHEMBL12762670	0.87	SLC29A1 (0.35)	—
SCHEMBL12570168	0.86	SLC29A1 (0.33)	—
SCHEMBL12762693	0.86	ADRA2A (0.33)	ADRA2ADRD5DRD3P2RY6
SCHEMBL12570219	0.86	ADRA2A (0.33)	ADRA2ADRD5DRD3P2RY6
SCHEMBL12762666	0.86	SLC29A1 (0.33)	—
SCHEMBL12570159	0.85	SLC29A1 (0.36)	—
SCHEMBL12570172	0.83	SLC29A1 (0.33)	ADRA2ADRD5DRD3P2RY6
SCHEMBL12762669	0.83	SLC29A1 (0.33)	ADRA2ADRD5DRD3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8361727-B2	3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing	LASERGEN, INC. (US)	2013-01-29	—	—	US	disclosed
US-20110287427-A1	3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING	LASERGEN, INC. (US)	2011-11-24	—	—	US	disclosed