⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22303490 | 0.79 | — | — | |
| SCHEMBL13912546 | 0.75 | MEN1 (0.37) | — | |
| SCHEMBL49946 | 0.73 | KMT2A (0.57) | — | |
| SCHEMBL20413723 | 0.73 | KMT2A (0.39) | — | |
| SCHEMBL309844 | 0.73 | — | — | |
| SCHEMBL28308957 | 0.72 | L3MBTL1 (0.31) | — | |
| SCHEMBL8882941 | 0.72 | MAPK1 (0.33) | — | |
| SCHEMBL27691810 | 0.72 | MAPK1 (0.30) | — | |
| SCHEMBL5496667 | 0.72 | MAPK1 (0.30) | — | |
| SCHEMBL18861931 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437915-B | Crystal form of pyrrolo-heterocyclic derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118871442-A | Crystal form of fumarate of pyrrolo-heterocyclic derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-113518779-B | Thieno heterocyclic derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-113544131-B | Pyrrolo-heterocyclic derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-113825757-B | Substituted fused bicyclic derivatives, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-20230331731-A1 | CRYSTAL FORM OF PYRROLO HETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) | 2023-10-19 | — | — | US | disclosed |
| WO-2023185869-A1 | CRYSTALLINE FORM OF FUMARATE OF PYRROLOHETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |
| EP-4223758-A1 | CRYSTAL FORM OF PYRROLO HETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
| CN-116437915-A | Crystal form of pyrrolo-heterocyclic derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114315837-B | Crystalline forms of ERK inhibitors and methods of making the same | 江苏恒瑞医药股份有限公司 | 2023-06-16 | — | — | CN | disclosed |
| US-5194432-A | Drugs for treatment of infectious diseases; microbiocides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-16 | — | — | US | disclosed |
| US-5162520-A | Useful in the preparation of antimicrobial compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5108997-A | Microbiocides | FUJISAWA PHARMACEUTICALS CO., LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| US-4960766-A | SUBSTITUTED 2-PYRAZOLIOMETHYL GROUP AND A 7-(AMINOTHIAZOLYL) (ALKOXYIMINO)-ACETAMIDO GROUP CEPHALOSPORIN DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4927818-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0306863-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |
| CN-87106452-A | New cephalosporanic olefinic compound and preparation method thereof | — | 1988-05-04 | — | — | CN | disclosed |
| EP-0261615-A2 | Cephem compounds, processes for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-30 | — | — | EP | disclosed |
| EP-0223246-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |
| CN-86107947-A | New cephem compounds and preparation method thereof | — | 1987-05-27 | — | — | CN | disclosed |