SCHEMBL888315

SCHEMBL888315

CCOC(=O)C(COC)(CC(C)C)C1CCCC1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.40
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
METAP2 P50579 1/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888462 0.99 MMP8 (0.39) MMP8MEN1KMT2AMETAP2ALDH1A1
SCHEMBL888473 0.89 MMP8 (0.40) MMP8METAP2ALDH1A1THRBATM
SCHEMBL888521 0.88 NPSR1 (0.33) MMP8
SCHEMBL888266 0.87 MMP8 (0.39) MMP8MEN1KMT2AMETAP2ALDH1A1
SCHEMBL888551 0.87 NPSR1 (0.36) MMP8
SCHEMBL3824103 0.86 MEN1 (0.33) MMP8MEN1KMT2AMETAP2
SCHEMBL888303 0.81
SCHEMBL8167417 0.80 MEN1 (0.35) MEN1KMT2AALDH1A1THRBATM
SCHEMBL888496 0.79 NPSR1 (0.32)
SCHEMBL7785262 0.77 MMP8 (0.45) MMP8MEN1KMT2AMETAP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-6121483-A 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO K.K. (JP) 2000-09-19 US disclosed
US-6118019-A 3-alkoxypropionic ester derivative SHOWA DENKO K.K. (JP) 2000-09-12 US disclosed
US-6015867-A MIXTURES OF ORGANOALUMINUM COMPOUNDS, MAGNESIUM, TITANIUM AND HALOGEN COMPOUNDS WITH ELECTRON DONOR ESTER AS INTENSIFIER, NONTOXIC, SAFE, EFFICIENT SHOWA DENKO K.K. (JP) 2000-01-18 US disclosed
EP-0704424-B1 3-Alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO KK (JP) 1998-12-30 EP disclosed
EP-0704424-A1 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO KABUSHIKI KAISHA (JP) 1996-04-03 EP disclosed