Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | NAT1 | P18440 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883780 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8883464 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8757417 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8757631 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8881476 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8883477 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8881480 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8883480 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL9027659 | 0.79 | ALDH1A1 (0.52) | KDM4EALDH1A1PIM1PIM2MEN1 | |
| SCHEMBL8882806 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1PIM1PIM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639918-A | Intermediate compounds useful in the preparation of fungicidal compositions containing (benzylidene)-azolylmethyclycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-17 | — | — | US | disclosed |
| CN-1031971-C | (Benzylidene)-azolylmethylcycloalkane and use as fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-12 | — | — | CN | disclosed |
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | disclosed |
| US-5380743-A | Fungicidal compositions containing (benzylidene)-azolymethylcycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5256683-A | Plant protective agent 1H-1,2,4-triazolylmethylcycloalkane or -alkene benzylidene | RHONE-POULENC AGROCHIMIE (FR) | 1993-10-26 | — | — | US | disclosed |
| EP-0378953-A1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE-POULENC AGROCHIMIE (FR) | 1990-07-25 | — | — | EP | disclosed |