Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925570 | 0.87 | MAPT (0.59) | FADS1MAPTGAAHPGDALDH1A1 | |
| SCHEMBL11741492 | 0.86 | NPSR1 (0.49) | FADS1MAPTGAAEGFRABL1 | |
| SCHEMBL11738231 | 0.85 | FADS1 (0.53) | FADS1MAPTGAAHTR3EHTR3B | |
| SCHEMBL4054374 | 0.85 | MAPT (0.62) | FADS1MAPTGAAHTR3EHTR3B | |
| SCHEMBL4929938 | 0.82 | EGFR (0.53) | MAPTGAAROCK1HPGDEGFR | |
| SCHEMBL4930598 | 0.82 | CYP3A4 (0.48) | MAPTGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL31495027 | 0.80 | PTGS1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31723253 | 0.80 | FADS1 (0.47) | FADS1MAPTGAAHTR3EHTR3B | |
| SCHEMBL22231930 | 0.80 | FADS1 (0.47) | FADS1MAPTGAAHTR3EHTR3B | |
| SCHEMBL29454190 | 0.80 | FADS1 (0.47) | FADS1MAPTGAAHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661169-A | HAVE AFFINITY FOR VASOPRESSIN AND/OR OXYTOCIN RECEPTORS | SANOFI (FR) | 1997-08-26 | — | — | US | disclosed |
| US-5585394-A | INHIBITOR, ANTAGONIST OF VASOPRESSIN OR OXYTOCIN | SANOFI (FR) | 1996-12-17 | — | — | US | disclosed |
| EP-0694536-A1 | 1-Benzyl-1,3-dihydro-2H-benzimidazol-2-one derivatives, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-01-31 | — | — | EP | disclosed |
| CN-1106804-A | 1-Benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one derivatives | SANOFI SA (FR) | 1995-08-16 | — | — | CN | disclosed |
| EP-0636614-A1 | Derivatives of 1-benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1995-02-01 | — | — | EP | disclosed |