SCHEMBL888394

SCHEMBL888394

CC(C)N(CCNCO[SiH3])C(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5932747 0.78 MEN1 (0.48) MEN1KMT2AALDH1A1
SCHEMBL7367901 0.72 MEN1 (0.42) MEN1KMT2AALDH1A1
SCHEMBL13996765 0.70 MEN1 (0.40) MEN1KMT2AALDH1A1
SCHEMBL26274264 0.70 MEN1 (0.40) MEN1KMT2AALDH1A1
SCHEMBL22479347 0.70 MEN1 (0.40) MEN1KMT2AALDH1A1
SCHEMBL172548 0.70 MEN1 (0.40) MEN1KMT2AALDH1A1
SCHEMBL888596 0.70
SCHEMBL16668176 0.69 MEN1 (0.43) MEN1KMT2A
SCHEMBL24744949 0.68 MEN1 (0.39) MEN1KMT2AALDH1A1
SCHEMBL4124680 0.68 CYP2C19 (0.56) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2374821-B1 MANUFACTURING METHOD OF SOLID CATALYST COMPONENT AND OF CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2015-05-06 EP disclosed
US-8546290-B2 Solid catalyst component for olefin polymerization, manufacturing method, and catalyst and olefin polymer manufacturing method TOHO TITANIUM CO., LTD. (JP) 2013-10-01 US disclosed
US-20110269926-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD TOHO TITANIUM CO., LTD. (JP) 2011-11-03 US disclosed
EP-2374821-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD Toho Titanium CO., LTD. (JP) 2011-10-12 EP disclosed