⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142156 | 0.78 | CYP2C9 (0.36) | — | |
| SCHEMBL22393379 | 0.70 | CYP2C9 (0.52) | — | |
| SCHEMBL27416973 | 0.70 | CYP2C9 (0.31) | — | |
| SCHEMBL888394 | 0.70 | MEN1 (0.36) | — | |
| SCHEMBL22393371 | 0.68 | PRMT3 (0.35) | — | |
| SCHEMBL27069755 | 0.67 | MEN1 (0.38) | — | |
| SCHEMBL28613919 | 0.66 | — | — | |
| SCHEMBL21496034 | 0.65 | — | — | |
| SCHEMBL17346388 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL6932464 | 0.64 | TDP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374821-B1 | MANUFACTURING METHOD OF SOLID CATALYST COMPONENT AND OF CATALYST FOR OLEFIN POLYMERIZATION | TOHO TITANIUM CO LTD (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-8546290-B2 | Solid catalyst component for olefin polymerization, manufacturing method, and catalyst and olefin polymer manufacturing method | TOHO TITANIUM CO., LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20110269926-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD | TOHO TITANIUM CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| EP-2374821-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD | Toho Titanium CO., LTD. (JP) | 2011-10-12 | — | — | EP | disclosed |