Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15406171 | 0.89 | ACP3 (0.58) | ACP3IDO1PDPK1HTTTAS1R3 | |
| SCHEMBL8093012 | 0.77 | SMN1; SMN2 (0.49) | ACP3 | |
| SCHEMBL28165745 | 0.73 | IDO1 (0.56) | ACP3IDO1PDPK1PIN1CA1 | |
| SCHEMBL28883743 | 0.73 | IDO1 (0.56) | ACP3IDO1PDPK1PIN1CA1 | |
| SCHEMBL10706985 | 0.69 | ACP3 (0.40) | ACP3CA2HTT | |
| SCHEMBL30734419 | 0.69 | ACP3 (0.56) | ACP3 | |
| SCHEMBL3248046 | 0.69 | ACP3 (0.56) | ACP3 | |
| SCHEMBL57132 | 0.69 | IDO1 (0.50) | ACP3IDO1PDPK1PIN1CYP11B2 | |
| SCHEMBL3418678 | 0.69 | IDO1 (0.50) | ACP3IDO1PDPK1PIN1CYP11B2 | |
| SCHEMBL21114381 | 0.69 | IDO1 (0.50) | ACP3IDO1PDPK1PIN1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686621-A | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases | ALCON LABORATORIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5464866-A | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases | ALCON LABORATORIES, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1994004143-A1 | SUBSTITUTED HYDRINDANES FOR THE TREATMENT OF ANGIOGENESIS-DEPENDENT DISEASES | ALCON LABORATORIES, INC. (US) | 1994-03-03 | — | — | WO | disclosed |