Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701088 | 0.82 | ACHE (0.52) | SMN1; SMN2CYP19A1KDM4EMAPTTSHR | |
| SCHEMBL8883969 | 0.77 | ACP3 (0.61) | ACP3 | |
| SCHEMBL1094690 | 0.76 | CYP19A1 (0.53) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL30707960 | 0.76 | CYP19A1 (0.53) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL385513 | 0.76 | CYP19A1 (0.53) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL6959969 | 0.75 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL13039620 | 0.74 | DRD2 (0.56) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL11819054 | 0.72 | CYP19A1 (0.53) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL1332811 | 0.72 | CYP19A1 (0.53) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL7518685 | 0.71 | CYP19A1 (0.49) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |