SCHEMBL8884

SCHEMBL8884

OB(O)c1cccc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 8/20 1.00
ALDH1A1 P00352 3/20 0.56
KDM4E B2RXH2 1/20 0.56
CA14 Q9ULX7 3/20 0.55
CA2 P00918 3/20 0.55
CA5A P35218 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
CA12 O43570 2/20 0.55
CYP3A4 P08684 2/20 0.55
CA9 Q16790 2/20 0.55
LMNA P02545 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MGLL Q99685 2/20 0.54
CA7 P43166 2/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA1 P00915 2/20 0.44
TSHR P16473 1/20 0.44
CYP2C9 P11712 1/20 0.44
HSD17B1 P14061 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28841000 0.97 ENPP2 (0.95) ENPP2ALDH1A1KDM4ECA14CA2
Bicarbonate SCHEMBL28665790 0.87 ENPP2 (0.76) ENPP2ALDH1A1KDM4ECA14CA2
SCHEMBL6614459 0.87 ENPP2 (0.76) ENPP2ALDH1A1KDM4ECA14CA2
SCHEMBL21115276 0.84 ENPP2 (0.72) ENPP2ALDH1A1KDM4ECA14CA2
SCHEMBL789866 0.83 ENPP2 (0.70) ENPP2ALDH1A1KDM4ECA14CA2
SCHEMBL26376806 0.80 ENPP2 (0.67) ENPP2ALDH1A1KDM4ECA14CA2
SCHEMBL16426165 0.80 ENPP2 (0.67) ENPP2ALDH1A1KDM4ECA14CA2
Resorcinol SCHEMBL9751786 0.77 CA12 (0.80) ENPP2ALDH1A1CA14CA2CA5A
SCHEMBL12182526 0.77 ENPP2 (0.62) ENPP2ALDH1A1CA14CA2CA5A
SCHEMBL17236455 0.77 ENPP2 (0.62) ENPP2ALDH1A1CA14CA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3087 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250177537-A1 AN ANTIBIOTIC, METHOD OF PREPARATION AND METHOD OF TREATMENT THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-06-05 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119978389-A Boron-containing oligomer for aging-resistant high-transparency addition-type silicon rubber, and preparation method and application thereof 中国科学院化学研究所 2025-05-13 CN claimed
CN-119751424-A Novel method for synthesizing Bei Shude mol of methanesulfonic acid 重庆圣华曦药业股份有限公司 2025-04-04 CN claimed
CN-117866443-B Flame-retardant silicone rubber material and preparation method and application thereof 池州聚石化学有限公司 2025-03-14 CN claimed
CN-118894728-B Silicon nitride ceramic and preparation method thereof 湖南湘瓷科艺有限公司 2025-03-11 CN claimed
CN-119285884-A Flame-retardant modified benzoxazine resin and preparation method thereof 四川大学 2025-01-10 CN claimed
CN-119143705-A Benzofuran lymph specific tyrosine phosphatase inhibitor and preparation method and application thereof 山东大学 2024-12-17 CN claimed
CN-118931242-A Acid-corrosion-resistant organic coating on surface of active metal and preparation method thereof 北京理工大学 2024-11-12 CN claimed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US claimed
WO-2007102126-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-09-13 WO claimed
EP-1395574-B1 4-(PHENYL-PIPERIDIN-4-YLIDENE-METHYL)-BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN, ANXIETY OR GASTROINTESTINAL DISORDERS ASTRAZENECA AB (SE) 2005-01-19 EP claimed
US-20040138259-A1 4-(phenyl-piperdin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders ASTRAZENECA AB (SE) 2004-07-15 US claimed
EP-1282616-B1 HYDROXYPHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATEMENT OF PAIN ASTRAZENECA AB (SE) 2004-06-16 EP claimed
EP-1395574-A1 4-(PHENYL-PIPERIDIN-4-YLIDENE-METHYL)-BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN, ANXIETY OR GASTROINTESTINAL DISORDERS AstraZeneca AB (SE) 2004-03-10 EP claimed
US-20030187022-A1 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain ASTRAZENECA AB (SE) 2003-10-02 US claimed
EP-1282616-A1 HYDROXYPHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATEMENT OF PAIN AstraZeneca AB (SE) 2003-02-12 EP claimed
WO-2002094810-A1 4-(PHENYL-PIPERIDIN-4-YLIDENE-METHYL)-BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN, ANXIETY OR GASTROINTESTINAL DISORDERS ASTRAZENECA AB (SE) 2002-11-28 WO claimed
WO-2001074804-A1 HYDROXYPHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATEMENT OF PAIN ASTRAZENECA AB (SE) 2001-10-11 WO claimed