Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.45 |
| ▸ | ANPEP | P15144 | 3/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270986 | 0.86 | ERAP1 (0.47) | CSNK1EERAP1ANPEPERAP2AOC3 | |
| SCHEMBL3506697 | 0.86 | ERAP1 (0.47) | CSNK1EERAP1ANPEPERAP2AOC3 | |
| Hydrochloric Acid SCHEMBL7435119 | 0.85 | ERAP1 (0.46) | CSNK1EERAP1ANPEPERAP2AOC3 | |
| SCHEMBL27630320 | 0.82 | CSNK1E (0.53) | CSNK1EERAP1ANPEPERAP2METAP2 | |
| SCHEMBL14159706 | 0.82 | ANPEP (0.50) | ERAP1ANPEPERAP2TSHRSLC6A2 | |
| SCHEMBL9076300 | 0.81 | CSNK1E (0.64) | CSNK1EANPEPLAP3RNPEPDNPEP | |
| SCHEMBL9076303 | 0.81 | CSNK1E (0.64) | CSNK1EANPEPLAP3RNPEPDNPEP | |
| SCHEMBL2486010 | 0.80 | ANPEP (0.49) | CSNK1EERAP1ANPEPERAP2METAP2 | |
| Hydrogen Peroxide SCHEMBL9581085 | 0.79 | TSHR (0.55) | ERAP1ANPEPERAP2AOC3TSHR | |
| Hydrochloric Acid SCHEMBL6891198 | 0.79 | ANPEP (0.47) | CSNK1EERAP1ANPEPERAP2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703076-A | TREATING HIV, AIDS | G. D. SEARLE & CO. (US) | 1997-12-30 | — | — | US | disclosed |
| US-5514801-A | TREATMENT OF AIDS | MONSANTO COMPANY (US) | 1996-05-07 | — | — | US | disclosed |