Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | RASGRP3 | Q8IV61 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | NAT1 | P18440 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884098 | 1.00 | AKR1C3 (0.47) | AKR1C3AKR1C1MAOBEGFRPIM1 | |
| SCHEMBL8885655 | 0.90 | AKR1C3 (0.51) | AKR1C3AKR1C1MAOBEGFRPIM1 | |
| SCHEMBL8885649 | 0.90 | AKR1C3 (0.51) | AKR1C3AKR1C1MAOBEGFRPIM1 | |
| SCHEMBL8884477 | 0.85 | HSD11B1 (0.51) | EGFRPIM1PIM2ACHEBCHE | |
| SCHEMBL8884465 | 0.85 | HSD11B1 (0.51) | EGFRPIM1PIM2ACHEBCHE | |
| SCHEMBL8852549 | 0.84 | AKR1C3 (0.46) | AKR1C3AKR1C1MAOBEGFRPIM1 | |
| SCHEMBL8159139 | 0.84 | AKR1C3 (0.46) | AKR1C3AKR1C1MAOBEGFRPIM1 | |
| SCHEMBL8883662 | 0.82 | AKR1C3 (0.45) | AKR1C3AKR1C1MAOBEGFRPIM1 | |
| SCHEMBL8158388 | 0.82 | AKR1C3 (0.45) | AKR1C3AKR1C1MAOBEGFRPIM1 | |
| SCHEMBL8852631 | 0.82 | AKR1C3 (0.45) | AKR1C3AKR1C1MAOBEGFRPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639918-A | Intermediate compounds useful in the preparation of fungicidal compositions containing (benzylidene)-azolylmethyclycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5380743-A | Fungicidal compositions containing (benzylidene)-azolymethylcycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5256683-A | Plant protective agent 1H-1,2,4-triazolylmethylcycloalkane or -alkene benzylidene | RHONE-POULENC AGROCHIMIE (FR) | 1993-10-26 | — | — | US | disclosed |