Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807523 | 0.84 | LMNA (0.32) | KCNH2 | |
| SCHEMBL2910656 | 0.76 | HDAC3 (0.43) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2376083 | 0.76 | HCRTR1 (0.41) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2376077 | 0.76 | HDAC3 (0.40) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3127823 | 0.76 | GRIN2B (0.42) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL270517 | 0.76 | HDAC3 (0.43) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL271043 | 0.76 | HCRTR1 (0.41) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8883642 | 0.75 | HDAC3 (0.42) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14378227 | 0.75 | HCRTR1 (0.41) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4106263 | 0.75 | GRIN2B (0.47) | GRIN2BGRIN1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625074-A | Sulphonylaminocarbonyltriazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |
| US-5532378-A | Sulphonylaminocarbonyltriazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0341489-B1 | Sulfonyl amino carbonyl triazolinones | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| US-5405970-A | Unique chemical intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| US-5241074-A | Hherbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| US-5094683-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-5057144-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| US-4990637-A | Chemical intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4927454-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-22 | — | — | US | disclosed |
| EP-0341489-A1 | Sulfonyl amino carbonyl triazolinones | BAYER AG (DE) | 1989-11-15 | — | — | EP | disclosed |
| US-4806147-A | Substituted 1-benzylsulphonyl-3-heteroaryl-(thio)urea herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| EP-0271780-A2 | Substituted 1-benzylsulfonyl-3-heteroaryl(thio) urea | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |