SCHEMBL8884585

SCHEMBL8884585

N[C@@]1(O)[C@@H](CO)O[C@@H](n2ccc(=O)[nH]c2=O)[C@@H]1F

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.52
SLC28A2 O43868 1/20 0.52
SLC29A1 Q99808 1/20 0.52
SLC28A3 Q9HAS3 1/20 0.52
P2RY2 P41231 9/20 0.41
P2RY14 Q15391 3/20 0.39
NT5E P21589 1/20 0.39
P2RY6 Q15077 7/20 0.39
P2RY4 P51582 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8884584 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL7520132 0.88 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL21490243 0.82 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL19987242 0.82 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL19987163 0.82 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9295095 0.81 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL31705067 0.80 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL31210192 0.79 SLC28A1 (0.56) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL20227082 0.78 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16023839 0.78 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684143-A ACID STABILITY; DNA AND RNA DUPLEXES AND TRIPLEXES LYNX THERAPEUTICS, INC. (US) 1997-11-04 US disclosed
WO-1997037691-A1 TELOMERASE INHIBITORS LYNX THERAPEUTICS, INC. (US) 1997-10-16 WO disclosed