SCHEMBL7520132

SCHEMBL7520132

N[C@@]1(O)[C@@H](CO)O[C@@H](n2ccc(=O)[nH]c2=O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.57
SLC28A2 O43868 1/20 0.57
SLC29A1 Q99808 1/20 0.57
SLC28A3 Q9HAS3 1/20 0.57
P2RY2 P41231 9/20 0.46
NT5E P21589 1/20 0.45
P2RY6 Q15077 8/20 0.43
P2RY4 P51582 3/20 0.42
P2RY14 Q15391 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8884585 0.88 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL8884584 0.88 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL31705067 0.87 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL31210192 0.86 SLC28A1 (0.56) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12151850 0.85 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL29998888 0.85 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16023839 0.85 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL29323337 0.85 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1376688 0.85 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12150018 0.85 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011359-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2025-01-09 US disclosed
US-20240150391-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORP (US) 2024-05-09 US disclosed
CN-117357548-A Oligonucleotide composition and method for preparing same 美国杰龙生物医药公司 2024-01-09 CN disclosed
EP-4286519-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORPORATION (US) 2023-12-06 EP disclosed
CN-111228288-B Oligonucleotide composition and method for preparing same 美国杰龙生物医药公司 2023-10-20 CN disclosed
EP-3137479-B1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORP (US) 2023-08-30 EP disclosed
US-11739114-B2 Oligonucleotide compositions and methods of making the same GERON CORPORATION (US) 2023-08-29 US disclosed
US-20220306676-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2022-09-29 US disclosed
US-11299511-B2 Oligonucleotide compositions and methods of making the same GERON CORPORATION (US) 2022-04-12 US disclosed
CN-111228288-A Oligonucleotide composition and method for preparing same 美国杰龙生物医药公司 2020-06-05 CN disclosed
CN-106459134-A Oligonucleotide composition and method for preparing same 美国杰龙生物医药公司 2017-02-22 CN disclosed
US-20150337314-A1 Oligonucleotide Compositions and Methods of Making the Same BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2015-11-26 US disclosed
WO-2015168310-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORPORATION (US) 2015-11-05 WO disclosed
EP-0882059-B1 SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3-'P5'- PHOSPHORAMIDATES LYNX THERAPEUTICS INC (US) 2002-02-06 EP disclosed
US-5859233-A PROTECTED 3'-AMINO GROUP-5'-PHOSPHORAMIDITE MONOMERS FOR USE IN SOLID PHASE SYNTHESIS, FORMING A STABLE, NUCLEASE RESISTANCE DNA LYNX THERAPEUTICS, INC. (US) 1999-01-12 US disclosed
EP-0882059-A1 SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3-'P5'- PHOSPHORAMIDATES LYNX THERAPEUTICS, INC. (US) 1998-12-09 EP disclosed
US-5824793-A ACTIVATING A 3'-DEPROTECTED AMINONUCLEOSIDE-5-PHOSPHORAMIDITE WITH TETRAZOLE AND REACTING WITH A 3'-PROTECTED AMINONUCLEOSIDE-5-PHOSPHORAMIDITE; OXIDATION OF THE PHOSPHORUS; LYNX THERAPEUTICS, INC. (US) 1998-10-20 US disclosed
US-5684143-A ACID STABILITY; DNA AND RNA DUPLEXES AND TRIPLEXES LYNX THERAPEUTICS, INC. (US) 1997-11-04 US disclosed
WO-1997037691-A1 TELOMERASE INHIBITORS LYNX THERAPEUTICS, INC. (US) 1997-10-16 WO disclosed
WO-1997031009-A1 SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3'→P5' PHOSPHORAMIDATES LYNX THERAPEUTICS, INC. (US) 1997-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150337314-A1 Oligonucleotide Compositions and Methods of Making the Same RNGTT, NSUN2, POLN SLC28A1 322/4885SLC28A2 273/4885SLC29A1 367/4885
US-11739114-B2 Oligonucleotide compositions and methods of making the same RNGTT, NSUN2, POLN SLC28A1 322/4885SLC28A2 273/4885SLC29A1 367/4885
US-20220306676-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME RNGTT, NSUN2, POLN SLC28A1 322/4885SLC28A2 273/4885SLC29A1 367/4885
US-11299511-B2 Oligonucleotide compositions and methods of making the same RNGTT, NSUN2, POLN SLC28A1 322/4885SLC28A2 273/4885SLC29A1 367/4885
US-20240150391-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME RNGTT, NSUN2, POLN SLC28A1 303/4885SLC28A2 278/4885SLC29A1 361/4885
US-20250011359-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME RNGTT, NSUN2, POLN SLC28A1 303/4885SLC28A2 278/4885SLC29A1 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.