Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886570 | 0.99 | DRD2 (0.43) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| SCHEMBL8885993 | 0.99 | DRD2 (0.43) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| Bromide SCHEMBL8885601 | 0.98 | DRD2 (0.42) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| SCHEMBL8884391 | 0.94 | DRD2 (0.42) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| Bromide SCHEMBL8884224 | 0.93 | DRD2 (0.42) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| SCHEMBL8885003 | 0.90 | DRD2 (0.49) | DRD2DRD1DRD3HTR1A | |
| Bromide SCHEMBL8884952 | 0.89 | DRD2 (0.49) | DRD2DRD1DRD3HTR1A | |
| SCHEMBL8884370 | 0.87 | DRD2 (0.45) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| SCHEMBL8886844 | 0.86 | DRD2 (0.43) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| SCHEMBL8884899 | 0.84 | DRD2 (0.43) | DRD2DRD1ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674909-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | ZAMBON GROUP (IT) | 1997-10-07 | — | — | US | disclosed |